Nexus of Pathophysiology and Therapeutics (NPT) is an international, peer-reviewed journal publishing research in pathophysiology, biomedical sciences, pharmacology, and therapeutics, with a focus on disease mechanisms and clinical applications.
Nexus of Pathophysiology and Therapeutics (NPT) is an international, peer-reviewed, open-access journal dedicated to advancing high-quality research across clinical and translational science, diagnostics, biomarkers, pathophysiology, disease biology, pharmacology, therapeutics, laboratory and biomedical sciences, immunology, inflammation, infectious diseases, toxicology, and natural products and therapeutic modulation.
NPT provides a multidisciplinary platform for researchers investigating human diseases and relevant experimental models from complementary clinical, biological, pharmacological, diagnostic, and therapeutic perspectives. The journal welcomes research that contributes to the diagnosis, prognosis, prevention, monitoring, and treatment of disease, as well as the development and evaluation of therapeutic interventions and biomedical approaches with clear relevance to disease mechanisms or clinical application.
A central focus of NPT is to connect disease biology and pathophysiology with diagnosis, pharmacological intervention, and therapeutic application. The journal therefore welcomes clinical and translational studies, diagnostic and prognostic research, biomarker studies, pharmacological and therapeutic investigations, laboratory-based research, toxicological and drug-safety studies, natural products research, and molecular, cellular, mechanistic, experimental, and computational studies that address meaningful biomedical or clinical questions.
NPT particularly values studies that are scientifically rigorous, methodologically sound, biologically or clinically meaningful, and capable of advancing knowledge or informing future research and practice. The journal encourages interdisciplinary and international research that connects different levels of biomedical investigation, from fundamental disease mechanisms and experimental models to clinical research and therapeutic application.
The mission of NPT is to connect disease science with clinical application and therapeutic innovation by providing a trusted platform for the dissemination of rigorous biomedical, pharmacological, diagnostic, and clinical research.
Through this approach, NPT seeks to contribute to a deeper understanding of disease mechanisms, improved diagnostic and prognostic approaches, more effective therapeutic strategies, and meaningful advances in biomedical and clinical practice.
NPT welcomes contributions from researchers across medicine, pharmacy, pharmacology, clinical and laboratory sciences, biomedical sciences, pathophysiology, molecular and cellular biology, immunology, infectious diseases, toxicology, natural products, and related disciplines.
The journal encourages interdisciplinary collaboration and international participation across diverse areas of biomedical, clinical, diagnostic, pharmacological, and therapeutic research.
NPT is committed to rigorous peer review, editorial independence, research integrity, publication ethics, transparency, and responsible scientific communication.
Manuscripts are evaluated according to their scientific quality, methodological rigor, originality, relevance, ethical integrity, and suitability for the journal, with assessment criteria tailored to the design and objectives of each study.
NPT supports transparent and responsible scholarly communication and follows established principles of publication ethics and research integrity throughout the editorial and publication process.
By bringing together clinical and translational research, diagnostics, biomarkers, pathophysiology, disease biology, pharmacology, therapeutics, laboratory sciences, and related biomedical disciplines, NPT aims to serve as a scientific nexus connecting disease mechanisms, evidence, diagnosis, and therapeutic progress.