This is the official journal for mechanistic pathophysiology and translational therapeutic research, and a leading journal advancing the mechanistic understanding of disease and translating molecular and cellular insights into therapeutic innovation and precision medicine.
About Journal

Nexus of Pathophysiology & Therapeutics Journal (NPT) is an international, peer-reviewed, open-access journal dedicated to advancing mechanistic understanding of disease biology and translating these insights into therapeutic innovations that improve patient care and clinical outcomes.

The journal provides a cross-disciplinary platform for research spanning molecular and cellular biology, pharmacology, experimental medicine, computational science, and clinical investigation. NPT fosters interdisciplinary approaches that bridge fundamental discovery and applied therapeutic development, with a strong emphasis on translational relevance and real-world impact.

NPT prioritizes studies that:

  • Elucidate mechanistic pathways underlying disease processes
  • Investigate therapeutic actions at molecular, cellular, and systems levels
  • Translate mechanistic findings into clinically actionable insights

All manuscripts undergo rigorous double-blind peer review, ensuring scientific integrity, methodological rigor, and mechanistic validity. The journal adheres to the highest standards of publication ethics, following internationally recognized guidelines, including COPE and ICMJE.

Operating under a continuous publication model, NPT ensures that accepted articles are rapidly disseminated and immediately accessible to the global scientific community. All content is published open access under the Creative Commons Attribution (CC BY 4.0) license, allowing unrestricted use, distribution, and reproduction with proper citation.

The journal welcomes contributions from researchers, clinicians, and healthcare professionals worldwide, providing a trusted platform for mechanistic and translational biomedical research. NPT aims to accelerate the translation of scientific discovery into therapeutic strategies, shaping the future of precision medicine, innovative therapies, and improved patient care.